BuSpar (buspirone) is commonly prescribed for patients diagnosed with any anxiety disorder. BuSpar is supposed to be taken two to three times a day - depending on the recommendations of your treatment care provide or directions on the label. It's always very important that you discuss all the aspects of your treatment with your health care provider to make sure you get all the benefits of taking BuSpar. The following drugs have been reported to interact with BuSpar and therefore must be reported to your health care provider right away: haloperidol, tranquilizers, itraconazole, diazepam, dexamethasone, erythromycin, sleeping pills, ketoconazole, MAO inhibitors, antihistamines, pain medications, sedatives, and anticonvulsants. Interactions have been reported, but they can be avoided if you discuss everything with your doctor before taking BuSpar for the first time. This drug can sometimes cause mild side effects - such as weakness, nervousness, drowsiness, fatigue, difficulty sleeping, stomach pain, depression, headache, dry mouth, excitement, upset stomach, diarrhea, lightheadedness, constipation, and vomiting, although some other ones can also be experienced sometimes.